BNFinder2: Faster Bayesian network learning and Bayesian classification

作者：Dojer Norbert^*; Bednarz Pawel; Podsiadlo Agnieszka; Wilczynski Bartek

来源：Bioinformatics, 2013, 29(16): 2068-2070.

DOI：10.1093/bioinformatics/btt323

Bayesian Networks (BNs) are versatile probabilistic models applicable to many different biological phenomena. In biological applications the structure of the network is usually unknown and needs to be inferred from experimental data. BNFinder is a fast software implementation of an exact algorithm for finding the optimal structure of the network given a number of experimental observations. Its second version, presented in this article, represents a major improvement over the previous version. The improvements include (i) a parallelized learning algorithm leading to an order of magnitude speed-ups in BN structure learning time; (ii) inclusion of an additional scoring function based on mutual information criteria; (iii) possibility of choosing the resulting network specificity based on statistical criteria and (iv) a new module for classification by BNs, including cross-validation scheme and classifier quality measurements with receiver operator characteristic scores.

• 出版日期2013-8-15