MARINE NATURAL OCCURRING 2,5-DIKETOPIPERAZINES: ISOLATION, SYNTHESIS AND OPTICAL PROPERTIES

作者：Laville Remi; Thanh Binh Nguyen; Moriou Celine; Petek Sylvain; Debitus Cecile; Al Mourabit Ali^*

来源：Heterocycles, 2015, 90(2): 1351-1366.

DOI：10.3987/COM-14-S(K)87

• Diketopiperazine
• Sponge
• Marine Metabolite
• Circular Dichroism

Seven 2,5-diketopiperazines (DKPs) were isolated from the Fijian marine sponge Acanthella cavernosa. NMR and circular dichroism (CD) comparison with synthetic L-L DKPs allowed us to determine unambiguously the L-L absolute configuration of the natural DKPs. This work initiated the setting up of an optical properties database of natural DKPs, including specific rotation and CD.

• 出版日期2015-1-1