摘要

Epilepsy is one of the most common neurological disorders. In the last decade a part of the unknown and often drug-resistant epilepsies could be explained by autoantibodies directed to neuronal cell surface antigens. In contrast to the classical onconeural antibodies, these antibodies are rarely associated with tumours and the related diseases respond better to immunotherapies. Furthermore, it is believed that the antibodies directed to surface proteins have a direct pathogenic effect. New possibilities are thereby opened up in the treatment of these antibodies-mediated epilepsies.

  • 出版日期2014-12

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