An evaluation of in-office flexible fiber-optic biopsies for laryngopharyngeal lesions

作者：Lee Francisco; Smith Kristine A; Chandarana Shamir; Matthews T Wayne; Bosch J Douglas; Nakoneshny Steven C; Dort Joseph C^*

来源：Journal of Otolaryngology-Head & Neck Surgery, 2018, 47(1): 31.

DOI：10.1186/s40463-018-0275-x

• Endoscopy
• In-office biopsy
• Larynx
• Pharynx
• Lesion

Background: Operative endoscopy and flexible fiber-optic in-office tissue biopsy are common techniques to assess suspicious laryngopharyngeal lesions.
Methods: The primary outcome was the delay to the initiation of treatment. Secondary outcomes were delay to biopsy, histopathological diagnosis, and assessment at a multidisciplinary oncology clinic. A retrospective analysis was performed to assess the relative delays between these approaches to biopsy of laryngopharyngeal lesions.
Results: There were 114 patients in the study cohort; 44 in-office and 70 operative endoscopic biopsies). The mean delay from consultation to biopsy was 17.4 days for the operative endoscopy group and 1.3 days for the in-office group. The mean delay from initial otolaryngology consultation to initiation of treatment was 51.7 days and 44. 6 days for the operative endoscopy and in-office groups, respectively.
Conclusion: In-office biopsy reduced the time from initial consultation to biopsy. The temporal gains via in-office biopsy did not translate into faster access to treatment This outcome highlights the opportunity to improve access to treatment for patients with early diagnosis.

• 出版日期2018-5-9