New developments in immunotherapies for food allergy

作者：Chhiba Krishan Dilip; Singh Anne Marie; Bryce Paul J

来源：Immunotherapy, 2015, 7(8): 913-922.

DOI：10.2217/IMT.15.55

• food allergy
• immunological tolerance
• immunotherapy
• OIT
• omalizumab
• oral immunotherapy
• SLIT
• sublingual immunotherapy

Food allergy affects around 10% of the population. As the prevalence of food allergy continues to increase, disproportionately in children, new therapies for food allergy are being investigated. While there are no approved treatments for food allergy, immunotherapy facilitates significant desensitization and protection from accidental exposure. Nevertheless, current immunotherapies do not entirely nor permanently eliminate sensitivity to the food allergen. Since the rates of sustained unresponsiveness are significantly lower than desensitization, future therapies that enhance the rates of long-term tolerance in patients will catalyze progress in this field over the next 5-10 years.

• 出版日期2015
• 单位西北大学