A novel gammaherpesvirus isolated from a black-tailed prairie dog (Cynomys ludovicianus)

作者:Nagamine Brandy; Jones Leandro; Tellgren Roth Christian; Cavender Jacqueline; Bratanich Ana C*
来源:Archives of Virology, 2011, 156(10): 1835-1840.
DOI:10.1007/s00705-011-1024-x

摘要

A new gammaherpesvirus, tentatively named cynomys herpesvirus 1 (CynGHV-1), was isolated from a black-tailed prairie dog (Cynomys ludovicianus). CynGHV-1 replicated cytopathogenically to moderate titers in various cell lines. Ten kb of the CynGHV-1 genome was sequenced using degenerate PCR and genomic cloning. Sequence similarities were found to different genes from known gammaherpesviruses. Phylogenetic analysis suggested that CynGHV-1 was in fact a novel virus closely related to representatives of different genera and unclassified members of the subfamily Gammaherpesvirinae. However, CynGHV-1 could not be assigned to any particular genus and therefore remains unclassified.

  • 出版日期2011-10