Impact of Case Volumes on the Outcomes of Percutaneous Nephrolithotomy

作者：Opondo Dedan; Tefekli Ahmet; Esen Tarik; Labate Gaston; Sangam Kandasami; De Lisa Antonello; Shah Hemendra; de la Rosette Jean^*

来源：European Urology, 2012, 62(6): 1181-1187.

DOI：10.1016/j.eururo.2012.03.010

• Case volume
• Complications
• Operating time
• Outcomes
• PCNL
• Stone free
• Urinary stones

Background: Previous studies have demonstrated relationships between case volumes and outcomes in surgery. Little is known about the impact of case volumes on the outcomes of percutaneous nephrolithotomy (PCNL). %26lt;br%26gt;Objective: To investigate the influence of case volumes on the efficacy and safety outcomes of PCNL. %26lt;br%26gt;Design, setting, and participants: From November 2007 to December 2009, prospective data were collected by the Clinical Research Office of the Endourological Society from consecutive patients over a 1-yr period in 96 centers globally. Data of 3933 patients in the Global PCNL study database were included in this study. %26lt;br%26gt;Outcome measurements and statistical analysis: Patients were divided into low-and high-volume groups based on the median annual case volume of their respective treatment center. Preoperative characteristics and outcomes were compared between the two groups. Case volume was treated as a continuous variable. The relationship between case volume and stone-free (SF) rate, complication rate, and duration of hospital stay was explored using multivariate regression analysis. %26lt;br%26gt;Results and limitations: SF rates were higher in high-volume centers (82.5% vs 75.1%; p value %26lt;0.001). Complication rates were lower in high-volume centers (15.9% vs 21.7%; p value 0.002), whereas the mean (standard deviation [SD]) duration of stay was shorter in high-volume centers (3.4 [2.6] vs 4.9 [3.7] d; p value %26lt;0.001). SF rate increased with case volume, whereas complication rate and duration of stay diminished with increasing case volumes after adjusting for stone burden, urine culture status, American Society of Anesthesiologists score, and the presence of staghorn stones. The highest SF rates were observed in centers with %26gt;120 cases per year. %26lt;br%26gt;Conclusions: Centers that perform high numbers of PCNLs per year achieve better results. Both the efficacy and safety outcomes of PCNL improve with the number of surgeries performed in a given center per year.

• 出版日期2012-12