Accuracy of Equilibrium Magnetization Mapping in Sliced Two-Dimensional Spoiled Gradient-Recalled Echo Pulse Sequence With Variable Flip Angle

作者：Kuribayashi Hideto^*; Sekino Masaki; Minowa Takuya; Maitani Yoshie; Ohsaki Hiroyuki; Tsushima Shohji; Hirai Shuichiro; Ueda Masayuki; Katayama Yasuo

来源：Journal of Magnetic Resonance Imaging, 2013, 38(5): 1245-1250.

DOI：10.1002/jmri.24023

• equilibrium magnetization map
• M-0 map
• quantitative imaging
• slice profile
• T-1 map
• 2D SPGR-VFA

PurposeTo evaluate the accuracy of an equilibrium magnetization (M-0) map obtained using a two-dimensional (2D) spoiled gradient-recalled echo (SPGR) pulse sequence with variable flip angle (VFA). %26lt;br%26gt;Materials and MethodsSingle-slice 2D SPGR images of 4% agar gel phantoms with different gadolinium-diethylene triamine pentaacetic acid (Gd-DTPA) concentrations (0-1 mM) were obtained with a VFA (2-30 degrees). The 2D SPGR-VFA data were acquired with different repetition times (TRs; 7.8-117.2 ms), Gaussian and sinc RF pulses, and different field strengths (4.7, 7, and 9.4 Tesla). M-0 and T-1 maps were calculated from the 2D SPGR-VFA data. M-0 and T-1 values were compared with those calculated from free-relaxed 2D gradient-recalled echo (GRE) images and inversion recovery-prepared 2D SPGR images. The M-0 and T-1 slice profiles were also investigated. %26lt;br%26gt;ResultsConsistent M-0 values were obtained, regardless of the different Gd concentrations, TRs, and pulse sequences. The M-0 slice profiles calculated from the sliced SPGR-VFA data quantitatively reproduced those calculated from the free-relaxed sliced GRE. In contrast, the T-1 values calculated from the 2D SPGR-VFA data were underestimated at a high Gd concentration, short TR, and Gaussian RF pulse. %26lt;br%26gt;ConclusionM(0) values calculated from 2D SPGR-VFA images are highly quantitative. J. Magn. Reson. Imaging 2013;38:1245-1250.

• 出版日期2013-11
• 单位河北医科大学