摘要

In Pakistan, nickel is often detected as pervasive contaminant in aquatic environment, showing potential menace to both human health and environment. The objectives of our study were to determine the toxic impact of acute doses of heavy metal salt, nickel sulphate (NiSO4 center dot 7H(2)O) on serum electrolytes and arterial blood gases in freshwater cyprinid, Labeo rohita. The acute toxicity test revealed 96h LC50 values of 19.21 mg/L for NiSO4 center dot 7H(2)O for L. rohita. In this study, two groups, one control and other experimental, each of 12 juveniles, were utilized. Based on LC50 values, experimental group was exposed to 19.21 mg/L of nickel sulphate for 96h. The assessment of nickel toxicity effects was based on comparison of analyzed concentrations of serum electrolytes and arterial blood gases of experimental group with control. In nickel sulphate treated groups, serum hyponatremia, hypokalemia, hypocalcemia, hypermagnecemia, hyperammonemia and hypoxia were observed. Based on momentous deviations in serum electrolyte levels and in arterial blood gases in experimental groups, it is concluded that NiSO4 center dot 7H(2)O is an active toxicant for L. rohita.

  • 出版日期2014-8