Argon laser phototherapy could eliminate the damage effects induced by the ionizing radiation "gamma radiation" in irradiated rabbits

作者：Abdul Aziz Karolin Kamel^*; Tuorkey M J

来源：Journal of Photochemistry and Photobiology B: Biology , 2010, 99(1): 29-35.

DOI：10.1016/j.jphotobiol.2010.01.011

• Gamma irradiation
• Non-ionizing argon laser
• Reduced glutathione
• Glutathione peroxidase
• Glucose-6-phosphate dehydrogenase

The ionizing radiations could be taken in considerate as an integral part in our life, since, living organisms are actually exposed to a constant shower of ionizing radiations whether from the natural or artificial resources. The radio-protective efficiency of several chemicals has been confirmed in animal trails, whereas, due to their accumulative toxicity, their clinical utility is limited. Therefore, we aimed in the present work to investigate the possibility of using argon laser to recuperate the damaged tissues due to exposing to the ionizing radiation. The rabbits were used in this study, and they were designed as control, gamma irradiated, laser, and gamma plus laser groups. Lipid peroxidation, reduced glutathione (GSH), glutathione peroxidase (GSH-Px) and glucose-6-phosphate dehydrogenase (G-6-PD) in blood and liver were evaluated. As well as, the level of protein thiol was evaluated in the plasma among each group. Results of this study revealed the potential therapeutic performance of the treatment by laser argon to decline the damaging effect of the ionized radiation whether at systematic or local levels. In conclusion, argon laser therapy appears propitious protective effect against the hazard effects of gamma radiation.

• 出版日期2010-4-2