Decarboxylative C-H Arylation of Benzoic Acids under Radical Conditions

作者:Seo Sangwon; Slater Mark; Greaney Michael F*
来源:Organic Letters, 2012, 14(10): 2650-2653.
DOI:10.1021/ol3010694

摘要

A decarboxylative radical cyclization reaction has been developed for the synthesis of fluorenones. The reaction uses Ag(I)/K2S2O8 to oxidatively decarboxylate an aroylbenzoic acid to an aryl radical, which undergoes cyclization to afford fluorenone products in good yield.

  • 出版日期2012-5-18