A Pediatric Case of Metastatic Conventional Parosteal Osteosarcoma Treated With Multidrug Chemotherapy

作者:Nodomi Seishiro; Umeda Katsutsugu*; Okamoto Takeshi; Saida Satoshi; Hiramatsu Hidefumi; Watanabe Ken ichiro; Adachi Souichi; Heike Toshio
来源:Pediatric Blood and Cancer, 2016, 63(8): 1471-1473.
DOI:10.1002/pbc.26052

摘要

Parosteal osteosarcoma (POS) is conventionally a low-grade sarcoma with limited metastatic potential; however, the tumor occasionally transforms into a high-grade dedifferentiated POS, which commonly metastasizes to distant organs. The present report describes a rare pediatric case of conventional POS with no dedifferentiated component yet had multiple pulmonary metastases at initial diagnosis. Following limb-sparing surgery and osteosarcoma-oriented neoadjuvant chemotherapy, the patient received total resection of pulmonary metastases. Despite no treatment for pulmonary recurrence 1 year after adjuvant chemotherapy, the patient is alive with stable disease 4 years and 6 months after the initial diagnosis.

  • 出版日期2016-8