Nanowire-Based Electrode for Acute In Vivo Neural Recordings in the Brain

作者：Suyatin Dmitry B; Wallman Lars; Thelin Jonas; Prinz Christelle N; Jorntell Henrik; Samuelson Lars; Montelius Lars; Schouenborg Jens^*

来源：PLos One, 2013, 8(2): e56673.

DOI：10.1371/journal.pone.0056673

We present an electrode, based on structurally controlled nanowires, as a first step towards developing a useful nanostructured device for neurophysiological measurements in vivo. The sensing part of the electrode is made of a metal film deposited on top of an array of epitaxially grown gallium phosphide nanowires. We achieved the first functional testing of the nanowire-based electrode by performing acute in vivo recordings in the rat cerebral cortex and withstanding multiple brain implantations. Due to the controllable geometry of the nanowires, this type of electrode can be used as a model system for further analysis of the functional properties of nanostructured neuronal interfaces in vivo.

• 出版日期2013-2-19