Decarboxylative Thioamidation of Arylacetic and Cinnamic Acids: A New Approach to Thioamides

作者:Guntreddi Tirumaleswararao; Vanjari Rajeshwer; Singh Krishna Nand*
来源:Organic Letters, 2014, 16(14): 3624-3627.
DOI:10.1021/ol501482g

摘要

A new decarboxylative strategy has been developed for the synthesis of thioamides via a three-component reaction involving arylacetic or cinnamic acids, amines and elemental sulfur powder, without the need of a transition metal and an external oxidant.

  • 出版日期2014-7-18