摘要

Due to the micro scale of inner structure of microfluidic analytical chip, the fluid possesses high specific surface area as well as small diffusion distance which remarkably improves mass transfer rate and enhances sample pretreatment efficiency,such as diffusion or extraction separation before determination,. In this paper,the applications of two kinds of liquid-phase mass transfer between miscible phases or immiscible phases in microfluidic analytical chip are reviewed. Further microfabrication and integration based on liquid-phase mass transfer for more complex devices and wider range of functions are introduced. The difficulties in technique development and application tendency are also discussed.