Mitochondrial translocator protein (TSPO), astrocytes and neuroinflammation

作者:Chechneva Olga V; Deng Wenbin*
来源:Neural Regeneration Research, 2016, 11(7): 1056-1057.
DOI:10.4103/1673-5374.187027

摘要

<正>Mitochondrial translocator protein(TSPO)has been a somewhat mysterious player in searching for its true biological functions.TSPO is involved in mitochondrial cholesterol transport and steroids biosynthesis and predominantly expressed in steroid-synthesizing tissues including the central nervous system(CNS).However,recent findings using conditional knockout animal models contradict the long-held view that TSPO plays

  • 出版日期2016-7