Acyl homoserine lactone-based quorum sensing stimulates biofilm formation by Salmonella Enteritidis in anaerobic conditions

作者：de Almeida Felipe Alves; Pimentel Filho Natan de Jesus; Pinto Uelinton Manoel; Mantovani Hilario Cuquetto; de Oliveira Leandro Licursi; Dantas Vanetti Maria Cristina

来源：Archives of Microbiology, 2017, 199(3): 475-486.

DOI：10.1007/s00203-016-1313-6

• Adhesion
• Autoinducer
• Biofilm
• Cellular communication
• Furanone

Quorum sensing regulates a variety of phenotypes in bacteria including the production of virulence factors. Salmonella spp. have quorum sensing systems mediated by three autoinducers (AI-1, AI-2, and AI-3). The AI-1-mediated system is incomplete in that the bacterium relies on the synthesis of signaling molecules by other microorganisms. This study aimed to evaluate the influence of the AI-1 N-dodecanoyl-DL-homoserine lactone (C12HSL) on the growth, motility, adhesion, and biofilm formation of Salmonella enterica serovar Enteritidis PT4 578 on a polystyrene surface. Experiments were conducted at 37 degrees C in anaerobic tryptone soy broth supplemented with C12-HSL and/or a mixture of four synthetic furanones, at the concentration of 50 nM each. The planktonic growth, adhesion, swarming, and twitching motility were not altered in the presence of C12-HSL and/or furanones under anaerobic conditions. However, C12-HSL induced biofilm

• 出版日期2017-4