Allele frequencies for six miniSTR loci of Northwestern Chinese Han populations

作者:Bai, Xue; Cong, Bin*; Li, Shujin; Guo, Xia; Li, Xia; He, Lujun
来源:Journal of Forensic and Legal Medicine, 2009, 16(8): 469-471.
DOI:10.1016/j.jflm.2009.05.004

摘要

MiniSTR loci has demonstrated to be an effective approach to recover genetic information from degraded sample, due to the improved PCR efficiency of their reduced PCR product sizes. Allele frequencies and forensic parameters for the six miniSTR loci D10S1248, D2S441, D1S1677, D9S1122, D10S1435 and D17S1301 were investigated in 154 Northwestern Chinese Han populations. All loci showed a moderate degree of polymorphism with observed heterozygosity >0.6 and did not show departures from Hardy-Weinberg equilibrium for Northwestern Chinese Han populations. The accumulated powers of discrimination for the six loci were 0.999998.

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