Arrhythmia triggers in heart failure: The smoking gun of [Ca2+](i) dysregulation

作者：Aistrup Gary L; Balke C William; Wasserstrom J Andrew^*

来源：Heart Rhythm, 2011, 8(11): 1804-1808.

DOI：10.1016/j.hrthm.2011.06.012

• Calcium alternans
• Calcium cycling
• Calcium waves
• Heart failure

Among the most serious problems associated with heart failure is the increased likelihood of life-threatening arrhythmias. Both triggered and reentrant arrhythmias in heart failure may arise as a result of aberrant intracellular Ca cycling. This article presents some new ideas, based on recent studies, about how altered Ca cycling in heart failure might serve as the cellular basis for arrhythmogenesis.

• 出版日期2011-11
• 单位西北大学