Association between hemodynamic activity and motor performance in six-month-old full-term and preterm infants: a functional near-infrared spectroscopy study

作者：de Oliveira Suelen Rosa; Cabral de Paula Machado Ana Carolina; de Paula Jonas Jardim; Paiva de Moraes Paulo Henrique; Silverio Nahin Maria Juliana; Magalhaes Livia de Castro; Novi Sergio L.; Mesquita Rickson C.; de Miranda Debora Marques; Ferrarez Bouzada Maria Candida

来源：Neurophotonics, 2018, 5(1): 011016.

DOI：10.1117/1.NPh.5.1.011016

• near-infrared spectroscopy
• premature infant
• sensorimotor cortex
• infant development
• functional activation

This study aimed to assess task-induced activation in motor cortex and its association with motor performance in full-term and preterm born infants at six months old. A cross-sectional study of 73 sixmonth- old infants was conducted (35 full-term and 38 preterm infants). Motor performance was assessed using the Bayley Scales of Infant Development third edition-Bayley-III. Brain hemodynamic activity during motor task was measured by functional near-infrared spectroscopy (fNIRS). Motor performance was similar in full-term and preterm infants. However, differences in hemodynamic response were identified. Full terms showed a more homogeneous unilateral and contralateral activated area, whereas in preterm-born the activation response was predominantly bilateral. The full-term group also exhibited a shorter latency for the hemodynamic response than the preterm group. Hemodynamic activity in the left sensorimotor region was positively associated with motor performance measured by Bayley-III. The results highlight the adequacy of fNIRS to assess differences in task-induced activation in sensorimotor cortex between groups. The association between motor performance and the hemodynamic activity require further investigation and suggest that fNIRS can become a suitable auxiliary tool to investigate aspects of neural basis on early development of motor abilities.

• 出版日期2018-3