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摘要
Evaluation of the technical success, patient safety and technical effectiveness of magnetic resonance (MR)-guided microwave ablation of hepatic malignancies. Institutional review board approval and informed patient consent were obtained. Fifteen patients (59.8 years +/- 9.5) with 18 hepatic malignancies (7 hepatocellular carcinomas, 11 metastases) underwent MR-guided microwave ablation using a 1.5-T MR system. Mean tumour size was 15.4 mm +/- 7.7 (7-37 mm). Technical success and ablation zone diameters were assessed by post-ablative MR imaging. Technique effectiveness was assessed after 1 month. Complications were classified according to the Common Terminology Criteria for Adverse Events (CTCAE). Mean follow-up was 5.8 months +/- 2.6 (1-10 months). Technical success and technique effectiveness were achieved in all lesions. Lesions were treated using 2.5 +/- 1.2 applicator positions. Mean energy and ablation duration per tumour were 37.6 kJ +/- 21.7 (9-87 kJ) and 24.7 min +/- 11.1 (7-49 min), respectively. Coagulation zone short- and long-axis diameters were 31.5 mm +/- 10.5 (16-65 mm) and 52.7 mm +/- 15.4 (27-94 mm), respectively. Two CTCAE-2-complications occurred (pneumothorax, pleural effusion). Seven patients developed new tumour manifestations in the untreated liver. Local tumour progression was not observed. Microwave ablation is feasible under near real-time MR guidance and provides effective treatment of hepatic malignancies in one session. aEuro cent Planning, applicator placement and therapy monitoring are possible without using contrast enhancement aEuro cent Energy transmission from the generator to the scanner room is safely possible aEuro cent MR-guided microwave ablation provides effective treatment of hepatic malignancies in one session aEuro cent Therapy monitoring is possible without applicator retraction from the ablation site.
- 出版日期2017-4
