A surprising new route to 4-nitro-3-phenylisoxazole

作者：Hopf Henning; Mourad Aboul fetouh E^*; Jones Peter G

来源：Beilstein Journal of Organic Chemistry, 2010, 6: 68.

DOI：10.3762/bjoc.6.68

• cinnamyl alcohol
• furoxan derivatives
• isoxazole derivatives
• X-ray diffraction

A one-pot synthesis of 4-nitro-3-phenylisoxazole has been carried out by treatment of cinnamyl alcohol dissolved in acetic acid with sodium nitrite; in addition, 4-phenyl-3-furoxanmethanol was obtained in 40% yield.

• 出版日期2010-6-23