NIR-triggered drug release from switchable rotaxane-functionalized silica-covered Au nanorods

作者:Li Menghuan; Yan Hong; Teh Cathleen; Korzh Vladimir; Zhao Yanli*
来源:Chemical communications, 2014, 50(68): 9745-9748.
DOI:10.1039/C4CC02966F

摘要

An NIR-triggered drug delivery system was developed by capping photo-switchable azobenzene-based rotaxane onto Au nanorod-mesoporous silica core-shell hybrids. Drug release from the nanocarrier in zebrafish embryo models could be controlled remotely under NIR irradiation, showing significant drug spreading to the adjacent tissues.

  • 出版日期2014-9-4