Determinant factors of fertility outcomes after laparoscopic colorectal resection for endometriosis

作者：Darai Emile^*; Carbonnel Marie; Dubernard Gil; Lavoue Vincent; Coutant Charles; Bazot Marc; Ballester Marcos

来源：European Journal of Obstetrics & Gynecology and Reproductive Biology, 2010, 149(2): 210-214.

DOI：10.1016/j.ejogrb.2009.12.032

• Endometriosis
• Colorectal endometriosis
• Laparoscopy
• Fertility
• Pregnancy

Objective: The aims of this prospective study were to evaluate fertility, pregnancy outcomes and their determinant factors after laparoscopic segmental colorectal resection for endometriosis.
Study design: We studied 83 women who underwent colorectal resection for endometriosis. Thirty-nine women (47%) had an associated infertility and 51(61.4%) wished to conceive after surgery. Surgical route was exclusive laparoscopy in 77 cases (92.7%) and laparoconversion in 6 (7.3%).
Results: Twenty-nine pregnancies were obtained in 24 patients (43.6%) including 20 spontaneous (69%) and 9 by IVF (31%). The median time to conceive spontaneously was 6 months and 20 months by IVF. Among the 39 infertile women, 18 (46%) conceived during the study period. A relation was found between pregnancy rate and patient age (p = 0.02). Reduction in pregnancy rate was correlated to the presence of adenomyosis (p = 0.04) and high ASRM total score (p < 0.001) as well as exclusive laparoscopy compared to conversion to laparotomy for colorectal resection (p = 0.01).
Conclusion: Adenomyosis and conversion to laparotomy as well as patient age. ASRM score appeared determinant factors of fertility outcome.

• 出版日期2010-4