科研之友
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摘要
The lipid profiles of brain from 10- and 18-day-old chick embryo, 1-day-old chick, and adult chicken as well as of full-term fetus rat, 21-day-old male, young adult male, and pregnant female rats were analyzed by thin-layer chromatography and densitometry. The emphasis was on the major glycolipids of brain during myelination (i.e., galactocyl diglyceride (GDG) normal fatty acid and hydroxyl fatty acid ceramide monohexosides (n-CMH, h-CMH, respectively)), and sulfatides (S) as well as the choline lipids sphingomyelin (SM), phosphatidyl choline (PC) and the two species of phosphatidyl ethanolamine plasmalogen (PE(1) and PE(2)). Ten-day-old chick embryo brain revealed a low concentration of glycolipids, which increased gradually during development, and reached the highest level in the adult chicken brain. Rat brain did not begin to show the presence of these glycolipids until 21 days old. In addition, PE (i.e., PE(1) and PE(2)) was shown to be the only alkenyle phospholipid in all samples analyzed. PE(2) was shown to correlate with the myclination process. PC and SM were also present. SM concentration was very low in 1-day-old chick and 21-day-old rat brains and increased gradually, reaching its highest level in the adult chicken and rat brains.
- 出版日期2011-8
