A turn-on fluorescent formaldehyde probe regulated by combinational PET and ICT mechanisms for bioimaging applications

作者：Yang, Xueling; He, Longwei; Xu, Kaixin; Yang, Yunzhen; Lin, Weiying^*

来源：Analytical Methods, 2018, 10(25): 2963-2967.

DOI：10.1039/c8ay00849c

• AZA-COPE REACTION
• LIVING CELLS
• MONITORING FORMALDEHYDE
• CANCER
• PERSPECTIVE
• TISSUES
• BRAIN
• SERUM

An illuminating formaldehyde-responsive fluorescence probe (Naph-FA) with a turn-on emission signal was rationally designed and synthesized. The reaction-based probe undergoes successive condensation, 2-aza-Cope rearrangement and hydrolysis processes in response to formaldehyde, and the fluorescence signal was regulated by combinational PET and ICT mechanisms.

• 出版日期2018-7-7
• 单位济南大学