Neopeapyran, an unusual furo[2,3b]pyran analogue and turnagainolide C from a soil Streptomyces sp S2236

作者：Zhou, Hao; Yang, Ya-Bin; Duan, Rong-Ting; Yang, Xue-Qiong; Zhang, Ju-Cheng; Xie, Xiao-Guang; Zhao, Li-Xing; Ding, Zhong-Tao^*

来源：Chinese Chemical Letters, 2016, 27(7): 1044-1047.

DOI：10.1016/j.cclet.2016.03.018

• Streptomyces sp.
• Furo[2,3b]pyran analogue
• Cyclopeptide
• Structure elucidation
• Antimicrobial activity

Neopeapyran (1), an unusual furo[2,3b]pyran analogue, together with a new cyclopeptide, turn-againolide C (2), were isolated from Streptomyces sp. S2236 associated with the rhizosphere soil of Panax notoginseng. The planar structure and relative configuration of neopeapyran (1) were elucidated on the basis of spectroscopic techniques, while the absolute configuration was determined by TDDFT calculation. The absolute configuration of turnagainolide C (2) was determined by partial hydrolysis, together with the advanced Marfey's method and spectroscopic analysis. The antimicrobial activities of these two compounds were also investigated.

• 出版日期2016-7
• 单位云南大学