The aromaticity/antiaromaticity continuum. 1. Comparison of the aromaticity of the dianion and the antiaromaticity of the dication of tetrabenzo[5.5]fulvalene via magnetic measures

作者：Mills NS^*; Benish M

来源：Journal of Organic Chemistry, 2006, 71(6): 2207-2213.

DOI：10.1021/jo051621j

[GRAPHICS]
The aromaticity of the dianion (2) and the antiaromaticity of the dication (3) of tetrabenzo[5.5] fulvalene have been evaluated through magnetic criteria, H-1 NMR shifts, nucleus-independent chemical shifts, NICS, and magnetic susceptibility exaltation, Lambda. The sum of the NICS values, using the GIAO (gauge-independent atomic orbital) method, for 2 is -35.2; that of 3 is +38.2, indicating the aromaticity of 2 and the antiaromaticity of 3. Calculation of magnetic Susceptibility exaltation using the CSGT (continuous set of gauge transformations) method gives a similar result, with Lambda of -81.8 ppm cgs for 2 and 95.8 ppm cgs for 3. The general validity of these values is suppoorted by excellent agreement between the NMR shifts calculated by the GIAO and CSGT methods with experimental shifts. Comparison of H-1 NMR shifts with those of model Compounds allows evaluation of the magnitude of the diatropic shift in 2 and paratropic shift in 3 and Supports their assignment as aromatic/antiaromatic, respectively. The agreement between calculated and experimental H-1 NMR shifts is excellent for 3 in the absence of counterions but much better for 2 when counterions are included. Inclusion of counterions in the evaluation of diatropic shift for 2 gave a smaller shift than in the absence of counterions, suggesting a decreased aromaticity. When counterions were included in the calculation of Lambda, the value was also decreased, suggesting a decreased aromaticity. This observation has important consequences in the use of experimental data for the evaluation of aromaticity, and presumably antiaromaticity, of anions since, in most cases, there will be close interaction with counterions.

• 出版日期2006-3-17