Manual morphometry of hippocampus.and amygdala in adults with attention-deficit hyperactivity disorder

作者：Nickel Kathrin^*; van Elst Ludger Tebartz; Perlov Evgeniy; Jitten Schachenrneier Renate; Beier Daniel; Endres Dominique; Goll Peter; Philipsen Alexandra; Maier Simon

来源：Psychiatry Research: Neuroimaging , 2017, 267: 32-35.

DOI：10.1016/j.pscychresns.2017.07.001

• Attention deficit hyperactivity disorder
• (ADHD)
• Hippocampus
• Amygdala

Previous studies have pointed to the involvement of limbic structures in the genesis of attention deficit hyperactivity disorder (ADHD). The present researchers manually segmented magnetic resonance images of 30 individuals with ADHD and 30 individually matched controls, focusing on amygdala and hippocampus volumes. Neither hippocampus nor amygdala volume differed significantly between individuals with and without ADHD. However, ADHD patients with higher hyperactivity scores had significantly smaller left amygdala volumes. This finding suggests that limbic alterations are significant in hyperactive symptoms in the pathophysiology of ADHD.

• 出版日期2017-9-30