摘要
The purpose of this study was to prepare human serum albumin (HSA) microspheres with Fe3O4 magnetic nanoparticles for tumor target therapy. Fe3O4 was obtained by liquid-phase coprecipitation; HSA-coated magnetic particles were attained by solidification at high temperature. The result was that nanosized Fe3O4 is a cubic crystal by XRD and the average size is 18.7 nm; the average size of HSA-coated magnetic particles is 341 nm. Fe3O4 magnetic nanoparticles coated with HSA can be used for targeted-drug carriers with target-orientation and sustained-release properties.
- 出版日期2007-6