Association between low renal function and tooth loss over 5 years

作者：Yoshihara Akihiro^*; Iwasaki Masanori; Miyazaki Hideo; Nakamura Kazutoshi

来源：Gerodontology, 2014, 31(2): 111-116.

DOI：10.1111/ger.12015

• epidemiology
• renal function
• tooth loss
• longitudinal study

ObjectivesThis longitudinal study evaluated the relationship between low renal function and tooth loss in elderly subjects. %26lt;br%26gt;Material and methodsSubjects comprised 406 female subjects (55-74years old) who agreed to participate in a baseline examination and a follow-up examination after 5years. Serum cystatin C levels were used to assess renal function. Multiple logistic regression analysis was used to evaluate the relationship between tooth loss and change in serum cystatin C levels over 5years. Tooth loss over 5years (0: no, 1: yes) was used as the dependent variable. Seven variables were used as independent variables, including change in serum cystatin C levels over 5years. %26lt;br%26gt;ResultsResults of multiple logistic regression analysis showed that cystatin C change over 5years, age, number of remaining teeth at baseline, number of sites with 4mm clinical attachment level at baseline and serum 25-hydroxyvitamin D levels at baseline were significantly associated with tooth loss. The odds ratio for tooth loss with cystatin C change over 5years was 7.70 (p=0.029). %26lt;br%26gt;ConclusionThis study indicates a relationship between serum cystatin C levels and number of missing teeth, and thus suggests that low renal function is associated with tooth loss.

• 出版日期2014-6