New dirhodium complex with activity towards colorectal cancer

作者：Frade Raquel F M^*; Candeias Nuno R; Duarte Catarina M M; Andre Vania; Duarte M Teresa; Gois Pedro M P; Afonso Carlos A M

来源：Bioorganic & Medicinal Chemistry Letters, 2010, 20(11): 3413-3415.

DOI：10.1016/j.bmcl.2010.04.002

• Dirhodium complex
• Human colon adenocarcinoma cells

A novel dirhodium complex (Rh-2(L-PheAla)(2)(OAc)(2) is reported with strong activity towards human colon adenocarcinoma cells. Its effect was not accompanied by generation of reactive oxygen species (ROS) neither by activation of caspase-3.

• 出版日期2010-6-1