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摘要
Dimeric alpha-aziridine aldehydes have been used as the aldehyde component in Ugi and Passerini reactions. The highly reactive mixed anhydride intermediate is subject to nucleophilic attack by the aziridine, leading to 'homo-Ugi' beta-acylaziridinyl-alpha-amino-amides. The products can be readily transformed into substituted lactones.
- 出版日期2012-9
