A Facile Route to the Synthesis of Coated Maghemite Nanocomposites for Hyperthermia Applications

作者：Ferk Gregor; Ban Irena^*; Stergar Janja; Makovec Darko; Hamler Anton; Jaglicic Zvonko; Drofenik Miha

来源：Acta Chimica Slovenica, 2012, 59(2): 366-374.

• Magnetite nanoparticles
• hyperthermia
• magnetic properties

CM-dextran-covered maghemite particles for applications in magnetic hyperthermia treatments were synthesized and their physical, magnetic and morphological properties were examined. Magnetic fluids were prepared and their heating pro per ties in an alternating magnetic field we re studied. The results re veal that the par tic le size and the thickness of the carboxy-methyl-dextran (CM-dextran) coatings have a decisive influence on the heating properties: specific absorption rate (SAR). The majority of the magnetic dissipation comes from the Neel relaxation, while the Brown contribution is small. A thermal steady state at the selected temperature (42 degrees C) can be achieved using synthesized maghemite particles with pro per par tic le morphology and by con trol ling the magnetic field intensity or the frequency.

• 出版日期2012