Antiepileptic drugs affect lipid oxidative markers-neuroprostanes and F-2-dihomo-isoprostanes- in patients with epilepsy: differences among first-, second-, and third-generation drugs by UHPLC-QqQ-MS/MS

作者：Medina Sonia; Carrasco Torres Ruben; Amor Isabel; Oger Camille; Galano Jean Marie; Durand Thierry; Villegas Martinez Irene; Auvin Stephane; Ferreres Federico; Gil Izquierdo Angel

来源：RSC Advances, 2016, 6(86): 82969-82976.

DOI：10.1039/c6ra15777g

This work show that treatment with new-generation AEDs reduces the excretion of NeuroPs/F2-dihomo-IsoPs to values similar to those in the control group, indicating a positive effect of these AEDs on the antioxidant status of epileptic patients.

• 出版日期2016