A general, modular approach to a new family of amine-substituted arylboronic acid saccharide chemosensors

作者:Schertzer Bryan M; Baker Sheila N; Diver Steven T*; Baker Gary A
来源:Australian Journal of Chemistry, 2006, 59(9): 633-639.
DOI:10.1071/CH05292

摘要

A general synthetic approach towards a class of water-soluble, high quantum yield fluorescent saccharide reporters using 6-morpholinonaphthalene-2-yl boronic acid as an illustrative case is reported. The strength and flexibility of this approach, which utilizes the Buchwald - Hartwig cross-coupling reaction, is further underscored by the preparation of several additional aminonaphthalenes in excellent yield, including one that bears a chiral unit.

  • 出版日期2006