Antiviral Activity of Clerodane from Baccharis patens Baker

作者:Montanha Jarbas A*; Schenkel Eloir P; Moellerke Patricia; Roehe Paulo M; Pires Viviane S; Venturi Caroline R
来源:Latin American Journal of Pharmacy, 2013, 32(4): 473-476.

摘要

A clerodane diterpene was isolated from the aerial parts of Baccharis patens Baker, which was identified as 2 alpha-hidroxy-hardwickiic acid by spectroscopic methods. Using the Yield reduction assay, this compound was active against herpes simplex virus type 1 (HSV-1) at 0.94, 0.47, and 0.23 mM, but did not show any virucidal activity.

  • 出版日期2013