Noninvasive Molecular Diagnosis of Human Visceral Leishmaniasis

作者：Vaish Manisha; Mehrotra Sanjana; Chakravarty Jaya; Sundar Shyam^*

来源：Journal of Clinical Microbiology, 2011, 49(5): 2003-2005.

DOI：10.1128/JCM.00130-11

Previously developed methods for noninvasive PCR diagnosis of visceral leishmaniasis (VL) have significant limitations. Diagnosis of VL using PCR and buccal swabs was evaluated in 307 subjects, including 148 patients confirmed to have VL. This method is simple and well tolerated and has good potential for development, showing 83% sensitivity with 90.56% specificity in control groups.

• 出版日期2011-5
• 单位河北医科大学