Autologous nerve anastomosis versus human amniotic membrane anastomosis A rheological comparison following simulated sciatic nerve injury

作者：Liu, Guangyao; Zhang, Qiao; Jin, Yan^*; Gao, Zhongli

来源：Neural Regeneration Research, 2011, 6(31): 2424-2428.

DOI：10.3969/j.issn.1673-5374.2011.31.005

• sciatic nerve injury
• anastomosis
• autologous nerve
• human amniotic membrane
• rheology

The sciatic nerve is biological viscoelastic solid, with stress relaxation and creep characteristics. In this study, a comparative analysis of the stress relaxation and creep characteristics of the sciatic nerve was conducted after simulating sciatic nerve injury and anastomosing with autologous nerve or human amniotic membrane. The results demonstrate that, at the 7 200-second time point, both stress reduction and strain increase in the human amniotic membrane anastomosis group were significantly greater than in the autologous nerve anastomosis group. Our findings indicate that human amniotic membrane anastomosis for sciatic nerve injury has excellent rheological characteristics and is conducive to regeneration of the injured nerve.

• 出版日期2011-12-15
• 单位吉林大学; 中日友好医院