Medical exposure to ionising radiation and the risk of brain tumours: Interphone study group, Germany

作者：Blettner Maria^*; Schlehofer Brigitte; Samkange Zeeb Florence; Berg Gabriele; Schlaefer Klaus; Schuz Joachim

来源：European Journal of Cancer, 2007, 43(13): 1990-1998.

DOI：10.1016/j.ejca.2007.06.020

• ionising radiation
• brain tumours
• risk factors
• aetiology
• epidemiology
• case-control study

Background: The role of exposure to low doses of ionising radiation in the aetiology of brain tumours has yet to be clarified. The objective of this study was to investigate the association between medically or occupationally related exposure to ionising radiation and brain tumours.
Methods: We used self-reported medical and occupational data collected during the German part of a multinational case-control study on mobile phone use and the risk of brain tumours (Interphone study) for the analyses.
Results: For any exposure to medical ionising radiation we found odds ratios (ORs) of 0.63 (95% confidence interval (CI) = 0.48-0.83), 1.08 (95% CI = 0.80-1.45) and 0.97 (95% CI = 0.54-1.75) for glioma, meningioma and acoustic neuroma, respectively. Elevated ORs were found for meningioma (OR 2.32, 95% CI: 0.90-5.96) and acoustic neuroma (OR 6.45, 95% CI: 0.62-67.16) for radiotherapy to the head and neck regions.
Conclusion: We did not find any significant increased risk of brain tumours for exposure to medical ionising radiation.

• 出版日期2007-9
• 单位河北医科大学