Deficient maternal zinc intake-but not folate-is associated with lower fetal heart rate variability

作者：Spann Marisa N^*; Smerling Jennifer; Gustafsson Hanna; Foss Sophie; Altemus Margaret; Monk Catherine

来源：Early Human Development, 2015, 91(3): 169-172.

DOI：10.1016/j.earlhumdev.2015.01.007

• Zinc
• Folate
• Fetal heart rate variability

Objective: Few studies of maternal prenatal diet and child development examine micronutrient status in relation to fetal assessment
Methods: Twenty-four-hour dietary recall of zinc and folate and 20 min of fetal heart rate were collected from 3rd trimester pregnant adolescents.
Results: Deficient zinc was associated with less fetal heart rate variability. Deficient folate had no associations with HRV. Neither deficient zinc nor deficient folate was related to fetal heart rate.
Conclusions: These findings, from naturalistic observation, are consistent with emerging data on prenatal zinc supplementation using a randomized control design.
Practical Implication: Taken together, the findings suggest that maternal prenatal zinc intake is an important and novel factor for understanding child ANS development.

• 出版日期2015-3