A literature review on the patients with autoimmune diseases following vaccination against infections

作者：Liang Yan; Meng Fan Ya; Pan Hai Feng; Ye Dong Qing^*

来源：Human Vaccines & Immunotherapeutics, 2015, 11(9): 2274-2280.

DOI：10.1080/21645515.2015.1009337

• autoimmune diseases
• vaccination
• infections
• biologics

Due to immune abnormalities and the use of steroids and immunosuppressant treatment, patients with rheumatic diseases are susceptible to infections. Vaccination is one of the most important prevention tools in modern medicine. A discussion on risk-benefit or cost-benefit analysis, and advisory on individual vaccines or vaccination programs falls outside the scope of this review. In particularly, this review summarizes the knowledge about the effectiveness and safety vaccinations in patients with autoimmune inflammatory rheumatic diseases (AIIRD) treated with biologics. Finally, we aim to provide vaccination plans basis for clinical management of rheumatic patients depending upon prevaccination antibody titers, drug treatments and immunological potential.

• 出版日期2015-9-2
• 单位安徽医科大学