Allergic diseases, gene-environment interactions

作者：Renz H^*; Conrad M; Brand S; Teich R; Garn H; Pfefferle P I

来源：Allergy, 2011, 66: 10-12.

DOI：10.1111/j.1398-9995.2011.02622.x

• Allergic disease
• gene-environment interaction
• early intervention
• epigenetics

P>Allergic asthma develops in part from dysregulation of the innate and adaptive immune functions, particularly an imbalance in the Th2-driven adaptive immune response. This dysregulation is the result of complex interactions between genes and environment. These interactions occur both pre- and postnatally, providing opportunities for early interventions in immunological programming.

• 出版日期2011-7