A recyclable multi-substrates catalytic system for enantioselective reduction of ketones in water

作者：Zeror Saoussen; Collin Jacqueline^*; Fiaud Jean Claude; Zouioueche Louisa Aribi

来源：Journal of Molecular Catalysis A: Chemical , 2006, 256(1-2): 85-89.

DOI：10.1016/j.molcata.2006.04.038

• ruthenium
• enantioselective catalysis
• alcohols
• reduction
• catalyst recycling

Enantioselective reductions of a variety of aromatic ketones catalyzed by [RuCl2(p-cymene)](2) coordinated by N-phenyl-(L)-proline amide in water have been performed with high asymmetric inductions in several cases. The reusability of catalyst has been studied. A multi-substrate recycling of the catalyst afforded successively seven alcohols each with similar enantiomeric excess than the one recorded in a single run.

• 出版日期2006-8-18