The association of osteopenia with levels of serum 25-hydroxyvitamin D and HOMA-IR values

作者：Yoldemir T^*; Yavuz D G

来源：Climacteric, 2014, 17(3): 268-272.

DOI：10.3109/13697137.2013.823393

• POSTMENOPAUSE
• 25-HYDROXYVITAMIN D
• HOMA-IR
• INSULIN RESISTANCE

Objective To determine the association of osteopenia with levels of serum 25-hydroxyvitamin D and HOMA-IR values in postmenopausal women.
Methods One hundred healthy postmenopausal women were included in a cross-sectional study. Venous blood was collected after an overnight fast and 25-hydroxyvitamin D, glucose and insulin levels were measured. HOMA-IR was calculated. Bone mineral density was measured with a dual X-ray absorptiometer.
Results There was no difference in serum 25-hydroxyvitamin D levels and HOMA-IR values between the two groups. A weak positive correlation between serum 25-hydroxyvitamin D levels and osteopenia was detected. Insulin resistance had a weak negative association with osteopenia.
Conclusions The correlations between osteopenia and serum 25-hydroxyvitamin D levels and HOMA-IR values were weak among early postmenopausal women.

• 出版日期2014-6