Health Effects of Psidium guajava L. Leaves: An Overview of the Last Decade

作者：Diaz de Cerio Elixabet; Verardo Vito; Maria Gomez Caravaca Ana; Fernandez Gutierrez Alberto; Segura Carretero Antonio

来源：International Journal of Molecular Sciences, 2017, 18(4): 897.

DOI：10.3390/ijms18040897

• Psidium guajava L. (guava) leaves
• traditional medicine
• in vitro
• in vivo
• phenolic compounds
• pharmacology

Today, there is increasing interest in discovering new bioactive compounds derived from ethnomedicine. Preparations of guava (Psidium guajava L.) leaves have traditionally been used to manage several diseases. The pharmacological research in vitro as well as in vivo has been widely used to demonstrate the potential of the extracts from the leaves for the co-treatment of different ailments with high prevalence worldwide, upholding the traditional medicine in cases such as diabetes mellitus, cardiovascular diseases, cancer, and parasitic infections. Moreover, the biological activity has been attributed to the bioactive composition of the leaves, to some specific phytochemical subclasses, or even to individual compounds. Phenolic compounds in guava leaves have been credited with regulating blood-glucose levels. Thus, the aim of the present review was to compile results from in vitro and in vivo studies carried out with guava leaves over the last decade, relating the effects to their clinical applications in order to focus further research for finding individual bioactive compounds. Some food applications (guava tea and supplementary feed for aquaculture) and some clinical, in vitro, and in vivo outcomes are also included.

• 出版日期2017-4