Maternal Reporting of Prenatal Ultrasounds Among Women in the National Birth Defects Prevention Study

作者：Weedn Ashley E; Mosley Bridget S; Cleves Mario A; Waller D Kim; Canfield Mark A; Correa Adolfo; Hobbs Charlotte A^*

来源：Birth Defects Research Part A: Clinical and Molecular Teratology , 2014, 100(1): 4-12.

DOI：10.1002/bdra.23178

• prenatal ultrasound
• birth defects
• maternal report
• National Birth Defects Prevention Study
• prenatal diagnosis

BackgroundIncreased availability and usage of ultrasound screening have led to improved identification of fetal structural abnormalities prenatally. Few population-based studies have been published on prenatal detection for structural birth defects in the United States. The aim of this study is to determine the frequency of maternal reporting of abnormal prenatal ultrasounds for selected birth defects and to investigate associated maternal characteristics. %26lt;br%26gt;MethodsParticipants included 4013 mothers enrolled in the National Birth Defects Prevention Study who carried a fetus with at least one of 14 structural birth defects between 1997 and 2004. Frequencies of abnormal prenatal ultrasounds were based on maternal report and computed for isolated and multiple defects. Associations between maternal characteristics and abnormal prenatal ultrasounds were assessed using logistic regression. %26lt;br%26gt;ResultsOverall, 46% of participants reported an abnormal ultrasound. Infants with omphalocele, anencephaly, gastroschisis, and renal agenesis were more likely to have abnormal prenatal ultrasounds than those with cleft and limb abnormalities. Hispanic women were less likely to report abnormal prenatal ultrasounds of birth defects than Caucasians, as were women who had a body mass index30 kg/m(2) compared with those with a normal body mass index. %26lt;br%26gt;CONCLUSIONOf the 14 selected birth defects in this study, less than half were reported by mothers of affected infants to have had an abnormal ultrasound during pregnancy. The frequency of reporting abnormal prenatal ultrasounds varies by type of defect, maternal race/ethnicity, and maternal body mass index status. Birth Defects Research (Part A) 100:4-12, 2014.

• 出版日期2014-1