Nephrotic syndrome associated with invasive mole: a case report

作者：Yang Jae Won; Choi Seung Ok; Kim Bi Ro; Kim Young Sub; Yoo Jong Myoung; Eom Min Seob; Han Byoung Geun^*

来源：Nephrology Dialysis Transplantation, 2010, 25(6): 2023-2026.

DOI：10.1093/ndt/gfq148

• invasive mole
• minimal change disease
• nephrotic syndrome

Gestational trophoblastic disease describes a number of gynaecological tumours that originate in the trophoblast layer, including hydatidiform mole (complete or partial), placental site trophoblastic tumour, choriocarcinoma and gestational trophoblastic neoplasia (GTN). Invasive moles are responsible for most cases of localized GTN. Two cases of GTN previously reported in the literature exhibited membranous glomerulonephritis (MGN). However, histologic examinations in our case did not reveal evidence of MGN. Clinical features and pathologic findings were consistent with minimal change disease associated with an invasive mole. In the present case, we observed complete remission of nephrotic syndrome following removal of the invasive mole.

• 出版日期2010-6