Auditory aura in frontal opercular epilepsy: sounds from afar

作者：Thompson Stephen A; Alexopoulos Andreas; Bingaman William; Gonzalez Martinez Jorge; Bulacio Juan; Nair Dileep; So Norman K^*

来源：Epileptic Disorders, 2015, 17(2): 150-155.

DOI：10.1684/epd.2015.0742

• auditory aura
• frontal operculum
• perisylvian epilepsy
• ictal SPECT
• magnetoencephalography

Auditory auras are typically considered to localize to the temporal neocortex. Herein, we present two cases of frontal operculum/perisylvian epilepsy with auditory auras. Following a non-invasive evaluation, including ictal SPECT and magnetoencephalography, implicating the frontal operculum, these cases were evaluated with invasive monitoring, using stereoelectroencephalography and subdural (plus depth) electrodes, respectively. Spontaneous and electrically-induced seizures showed an ictal onset involving the frontal operculum in both cases. A typical auditory aura was triggered by stimulation of the frontal operculum in one. Resection of the frontal operculum and subjacent insula rendered one case seizure- (and aura-) free. From a hodological (network) perspective, we discuss these findings with consideration of the perisylvian and insular network(s) interconnecting the frontal and temporal lobes, and revisit the non-invasive data, specifically that of ictal SPECT.

• 出版日期2015-6