A novel one-pot three component approach to 6-substituted 2,4-diamino-1,3,5-triazines using nano-sized copper/zinc-modified MCM-41 (Cu/Zn-MCM-41) as a new heterogeneous mesoporous catalyst

作者：Shekouhy Mohsen; Moaddeli Ali; Khalafi Nezhad Ali^*

来源：Journal of Industrial and Engineering Chemistry, 2017, 50: 41-49.

DOI：10.1016/j.jiec.2017.01.001

• 6-Substituted 2,4-diamino-1,3,5-triazine
• Nano-sized copper/zinc-modified MCM-41
• Mesoporous catalyst
• Multi-component reaction
• One-pot synthesis

The nano-sized copper/zinc-modified MCM-41 (Cu/Zn-MCM-41) was successfully prepared and applied as a new heterogeneous mesoporous nano-catalyst in a more benign and novel one-pot three component strategy for the synthesis of 6-substituted 2,4-diamino-1,3,5-triazines from aryl-aldehydes, hydroxyl amine and 2-cyanoguanidine under microwave irradiation. Using this method, the major problems of previously reported methods (very low diversity of available starting materials and the production of explosive byproducts) have been solved and all desired products were obtained in good to excellent yields in very short times.

• 出版日期2017-6-25